Patients with xanthomas should be worked up with
lipid panels, but not those with xanthelasmas or xanthofibromas in the
sense of dermatofibromas. Those whose fasting serum is lipemic should
have a lipid panel, but the serum of a subject with high cholesterol
(but normal triglyceride) is not milky in appearance. The patient with
high cholesterol (>240 mg/dL) should have a lipid panel. Patients
with cholesterol levels between 200-240 mg/dL plus two other coronary
heart disease risk factors should also have a lipid panel.1
In addition to application in screening programs for evaluation of risk
factors for coronary arterial disease, lipid profiling may lead to
detection of some cases of hypothyroidism.
Primary hyperlipoproteinemia includes hypercholesterolemia, a direct risk factor for coronary heart disease.
includes nephrosis, renal failure, obesity, diabetes mellitus,
alcoholism, primary biliary cirrhosis, and other types of cholestasis.
Decreased lipids are found with some cases of malabsorption,
malnutrition, and advanced liver disease. In abetalipoproteinemia,
cholesterol is <70 mg/dL.